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Eprinomectin

Eprinomectin is a semi-synthetic avermectin that is clinically used to treat livestock and domestic animals; it exhibits anti-helminthic and anti-parasitic activities. Eprinomectin increases GABA release, causing neuromuscular paralysis in microbes and parasites.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18919929

Cas No.

123997-26-2

Purity

≥45%

Formula

B1a: C50H75NO14; B1b: C49H73NO14

Chemical Name

(4R)-4-(Acetylamino)-4-deoxy-avermectin B1

Synonym

Eprinex

Melting Point

163.3-165.7°C

Solubility

Soluble in methanol.

Appearance

White Crystalline Powder

Knaus M, Chester ST, Rosentel J, et al. Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel against larval and adult stages of the cat lungworm, Aelurostrongylus abstrusus. Vet Parasitol. 2014 Apr 28;202(1-2):64-8. PMID: 24703080.

Nazir T, Katoch R, Godara R, et al. Efficacy of eprinomectin pour-on against Rhipicephalus (Boophilus) microplus on buffaloes. J Parasit Dis. 2013 Oct;37(2):166-7. PMID: 24431562.

AZD5438