E64
E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1889806
| Cas No. |
66701-25-5 |
|---|---|
| Purity |
≥98% |
| Formula |
C15H27N5O5 |
| Formula Wt. |
357.41 |
| IUPAC Name |
(2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid |
| Appearance |
White Crystal Powder |
Quain MD, Makgopa ME, Márquez-García B, et al. Ectopic phytocystatin expression leads to enhanced drought stress tolerance in soybean (Glycine max) and Arabidopsis thaliana through effects on strigolactone pathways and can also result in improved seed traits. Plant Biotechnol J. 2014 Apr 22. [Epub ahead of print]. PMID: 24754628.
Lee YA, Nam YH, Min A, et al. Entamoeba histolytica-secreted cysteine proteases induce IL-8 production in human mast cells via a PAR2-independent mechanism. Parasite. 2014;21:1. PMID: 24502918.
Shin SP, Han SY, Han JE, et al. Expression and characterization of cathepsin L-like cysteine protease from Philasterides dicentrarchi. Parasitol Int. 2014 Apr;63(2):359-65. PMID: 24361286.
