Dolasetron
Dolasetron is an antiemetic that is clinically used to prevent chemotherapy-induced nausea and emesis. Dolasetron acts as an antagonist at 5-HT3 receptors.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1889047
| Cas No. |
115956-12-2 |
|---|---|
| Purity |
≥98% |
| Formula |
C19H20N2O3 |
| Formula Wt. |
324.37 |
| Solubility |
Soluble in water and ethanol. |
| Appearance |
White to off white powder |
Hsu ES. A review of granisetron, 5-hydroxytryptamine3 receptor antagonists, and other antiemetics. Am J Ther. 2010 Sep-Oct;17(5):476-86. PMID: 20844345.
Birmingham SD, Mecklenburg BW, Lujan E, et al. Dolasetron versus ondansetron as single-agent prophylaxis for patients at increased risk for postoperative nausea and vomiting: a prospective, double-blind, randomized trial. Mil Med. 2006 Sep;171(9):913-6. PMID: 17036618.
