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Diflubenzuron

Diflubenzuron is a benzoylurea insecticide that disrupts chitin synthesis, acting as an insect growth regulator. Diflubenzuron displays efficacy against Tribolium, Anopheles, Ascaris, and Haemonchus.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/1886634

Cas No.

35367-38-5

Purity

≥95%

Formula

C14H9ClF2N2O2

Formula Wt.

310.68

Chemical Name

N-(((4-chlorophenyl)amino)carbonyl)- 2,6-difluoro- benzamide

IUPAC Name

N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide

Synonym

Difluron; Dimilin; Duphacid; Micromite.

Melting Point

239°C

Solubility

Soluble in acetone (0.65 gm/100ml at 20oC), DMSO or methanol.

Appearance

White Crystal Powder

Merzendorfer H, Kim HS, Chaudhari SS, et al. Genomic and proteomic studies on the effects of the insect growth regulator diflubenzuron in the model beetle species Tribolium castaneum. Insect Biochem Mol Biol. 2012 Apr;42(4):264-76. PMID: 22212827.

Zhang J, Zhu KY. Characterization of a chitin synthase cDNA and its increased mRNA level associated with decreased chitin synthesis in Anopheles quadrimaculatus exposed to diflubenzuron. Insect Biochem Mol Biol. 2006 Sep;36(9):712-25. PMID: 16935220.

Fetterer RH, Urban JF Jr, Miller RW. Effects of the chitin synthesis inhibitor diflubenzuron on development of Ascaris suum and Haemonchus contortus. Vet Parasitol. 1989 Jul 15;32(2-3):181-92. PMID: 2505433.

AZD 7762