D-(+)-Neopterin
Neopterin is a pteridine metabolite of GTP. Neopterin is an endogenous biomarker of cellular immune response and oxidative stress. Increases in neopterin levels are associated with increases in ROS, autoimmune diseases, and viral or bacterial infections.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18855114
| Cas No. |
2009-64-5 |
|---|---|
| Purity |
≥98% |
| Formula |
C9H11N5O4 |
| Formula Wt. |
253.21 |
| Chemical Name |
2-Amino-6-(1,2,3-trihydroxypropyl)-4(3H)-pteridinone |
| IUPAC Name |
2-amino-6-(1,2,3-trihydroxypropyl)-1H-pteridin-4-one |
| Synonym |
Crithidia factor |
| Solubility |
Soluble in 1N hydrogen chloride. |
| Appearance |
Off White to yellow solid |
Ahmadzai H, Cameron B, Chui J, et al. Measurement of neopterin, TGF-β1 and ACE in the exhaled breath condensate of patients with sarcoidosis. J Breath Res. 2013 Dec;7(4):046003. PMID: 24091835.
Murr C, Widner B, Wirleitner B, et al. Neopterin as a marker for immune system activation. Curr Drug Metab. 2002 Apr;3(2):175-87. PMID: 12003349.
