Cypermethrin
Cypermethrin is a synthetic type II pyrethroid insecticide. Cypermethrin inhibits protein phosphatases, inducing nerve blockade and paralysis. This compound is neurotoxic and induces astrocyte injury in vitro.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18854736
| Cas No. |
52315-07-8 |
|---|---|
| Purity |
≥98% |
| Formula |
C22H19Cl2NO3 |
| Formula Wt. |
416.30 |
| Chemical Name |
3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane- carboxylic acid cyano(3-phenoxyphenyl)methyl ester |
| IUPAC Name |
[cyano-(3-phenoxyphenyl)methyl]3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate |
| Synonym |
Ammo; Arrivo; Basathrin; Cymbush; Demon; Ripcord |
| Melting Point |
60-80°C |
| Solubility |
Soluble in methanol, acetone, xylene or methylene dichloride. Insoluble in water. |
| Appearance |
Yellow or Light Brown homogeneous liquid |
Maurya SK, Mishra J, Tripathi VK, et al. Cypermethrin induces astrocyte damage: role of aberrant Ca(2+), ROS, JNK, P38, matrix metalloproteinase 2 and migration related reelin protein. Pestic Biochem Physiol. 2014 May;111:51-9. PMID: 24861934.
Gammon DW. Correlations between in vitro and in vivo mechanisms of pyrethroid insecticide action. Fundam Appl Toxicol. 1985 Feb;5(1):9-23. PMID: 2985459.
