Corynoline
Corynoline is an alkaloid compound originally found in Corydalis tubers that exhibits anticancer activity. Corynoline displays cytotoxicity against several types of cancers in vitro, including lung carcinoma, colon carcinoma, melanoma, and ovarian carcinoma cell lines. Corynoline also noncompetitively inhibits acetylcholinesterase (AChE) in vitro.
References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18853477
Cas No. |
18797-79-0 |
---|---|
Purity |
≥98% |
Formula |
C21H21NO5 |
Formula Wt. |
367.40 |
Appearance |
White to off white powder |
Choi SU, Baek NI, Kim SH, et al. Cytotoxic isoquinoline alkaloids from the aerial parts of Corydalis incisa. Arch Pharm Res. 2007 Feb;30(2):151-4. PMID: 17366734.
Kim DK. Inhibitory effect of corynoline isolated from the aerial parts of Corydalis incisa on the acetylcholinesterase. Arch Pharm Res. 2002 Dec;25(6):817-9. PMID: 12510831.