Corazonin
Corazonin is a highly conserved neuropeptide found in many insects. Corazonin is cardiostimulatory, playing a role in cardiac function. Additionally, corazonin promotes transfer of sperm and mating behavior through the activation of serotonergic neurons.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18853272
| Cas No. |
122984-73-0 |
|---|---|
| Purity |
≥95% |
| Formula |
C62H86N18O19 |
| Formula Wt. |
1369.49 |
| IUPAC Name |
N-[1-[[1-[[1-[[2-[[1-[[1-[(1,4-diamino-1,4-dioxobutan-2-yl)amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]-2-[[2-[[3-hydroxy-2-[(5-oxopyrrolidine-2-carbonyl)amino]butanoyl]amino]-3-phenylpropanoyl]amino]pentanediamide |
| Appearance |
White to off white powder |
Tayler TD, Pacheco DA, Hergarden AC, et al. A neuropeptide circuit that coordinates sperm transfer and copulation duration in Drosophila. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20697-702. PMID: 23197833.
Hillyer JF, Estévez-Lao TY, Funkhouser LJ, et al. Anopheles gambiae corazonin: gene structure, expression and effect on mosquito heart physiology. Insect Mol Biol. 2012 Jun;21(3):343-55. PMID: 22404523.
