Climbazole
Climbazole is an antifungal compound that displays antimicrobial activity against Malassezia, treating dandruff and eczema. Like other similar compounds, climbazole likely inhibits 14-α demethylase.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18852395
| Cas No. |
38083-17-9 |
|---|---|
| Purity |
≥98% |
| Formula |
C15H17ClN2O2 |
| Formula Wt. |
292.76 |
| IUPAC Name |
1-(4-chlorophenoxy)-1-imidazol-1-yl-3,3-dimethylbutan-2-one |
| Synonym |
Baypival |
| Melting Point |
98-99°C |
| Appearance |
White Crystal Powder |
Turner GA, Matheson JR, Li GZ, et al. Enhanced efficacy and sensory properties of an anti-dandruff shampoo containing zinc pyrithione and climbazole. Int J Cosmet Sci. 2013 Feb;35(1):78-83. PMID: 22970742.
Schmidt A. In vitro activity of climbazole, clotrimazole and silver-sulphadiazine against isolates of Malassezia pachydermatis. Zentralbl Veterinarmed B. 1997 Jun;44(4):193-7. PMID: 9230670.
