CAY10505
CAY10505 is an inhibitor of p110γ PI3K. CAY10505 increases endothelial relaxation, normalizes levels of glutathione, nitrate, and nitrite, and alters the vascular endothelial lining in hypertensive rats, improving vascular endothelial dysfunction.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1884853
| Cas No. |
1218777-13-9 |
|---|---|
| Purity |
≥98% |
| Formula |
C14H8FNO3S |
| Formula Wt. |
289.28 |
| IUPAC Name |
(5E)-5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-1,3-thiazolidine-2,4-dione |
| Appearance |
Orange Powder |
Tyagi S, Sharma S, Budhiraja RD. Effect of phosphatidylinositol 3-kinase-γ inhibitor CAY10505 in hypertension, and its associated vascular endothelium dysfunction in rats. Can J Physiol Pharmacol. 2012 Jul;90(7):881-5. PMID: 22731503.
