Bursin
Bursin is a tripeptide that induces B-cell differentiation. Bursin’s immunostimulatory activity allows it to be used as an adjuvant for immunizations.
References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18845270
Cas No. |
60267-34-7 |
---|---|
Purity |
≥95% |
Formula |
C14H25N7O3 |
Formula Wt. |
339.39 |
IUPAC Name |
(2S)-2,6-diamino-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(4H-imidazol-4-yl)-1-oxopropan-2-yl]hexanamide |
Synonym |
Bursopoietin; Lys-his-gly-NH2 |
Wang C, Wen WY, Su CX, et al. Bursin as an adjuvant is a potent enhancer of immune response in mice immunized with the JEV subunit vaccine. Vet Immunol Immunopathol. 2008 Apr 15;122(3-4):265-74. PMID: 18191231.
Otsubo Y, Chen N, Kajiwara E, et al. Role of bursin in the development of B lymphocytes in chicken embryonic Bursa of Fabricius. Dev Comp Immunol. 2001 Jun-Jul;25(5-6):485-93. PMID: 11356228.