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Biopterin

Biopterin is an endogenous pterin coenzyme that acts as a cofactor for amino acid hydroxylases that produce neurotransmitters and bind NOS to stimulate NO release.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18844327

Cas No.

22150-76-1

Purity

≥98%

Formula

C9H11N5O3

Formula Wt.

237.22

Chemical Name

2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4(1H)- pteridinone

IUPAC Name

2-amino-6-(1,2-dihydroxypropyl)-1H-pteridin-4-oneInChI: InChI=1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h2-3,6,15-16H,1H3,(H3,10,11,13,14,17)

Synonym

Pterin HB2, L-Erythro-Biopterin, L-Biopterin.

Melting Point

250-280°C (chars)

Solubility

Soluble in alcohol, ether, acetone, or benzene.

Appearance

Faint yellow to faint brown powder

Longo N. Disorders of biopterin metabolism. J Inherit Metab Dis. 2009 Jun;32(3):333-42. Erratum in: J Inherit Metab Dis. 2009 Jun;32(3):457. PMID: 19234759.

Li HY, Yao YM, Shi ZG. The biological effect of tetrahydrobiopterin and its potential role in sepsis. Sheng Li Ke Xue Jin Zhan. 1999 Oct;30(4):303-8. PMID: 12532822.

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