Berteroin
Berteroin is a Erucin homolog that may exhibit antioxidative and anti-androgenic activities. Berteroin is an isothiocyanate (ITC) compound that decreases androgen receptor levels in prostate cancer cells. Berteroin also displays anti-inflammatory properties, decreasing LPS-induced release of pro-inflammatory cytokines in macrophages.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18843658
| Cas No. |
4430-42-6 |
|---|---|
| Purity |
≥97% |
| Formula |
C7H13NS2 |
| Formula Wt. |
175.43 |
| Chemical Name |
1-Isothiocyanato-5-(methylthio)-pentane |
| IUPAC Name |
1-isothiocyanato-5-methylsulfanylpentane |
| Synonym |
5-Methylthiopentyl isothiocyanate |
| Melting Point |
155-156°C |
| Solubility |
Soluble in DMSO, ethanol, or chloroform. |
| Appearance |
Yellow Liquid |
Jung YJ, Jung JI, Cho HJ, et al. Berteroin present in cruciferous vegetables exerts potent anti-inflammatory properties in murine macrophages and mouse skin. Int J Mol Sci. 2014 Nov 11;15(11):20686-705. PMID: 25393510.
Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144.
Kim SH, Singh SV. D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells. Mol Cancer Ther. 2009 Jul;8(7):1946-54. PMID: 19584240.
