5-Methoxyindole
5-Methoxy indole is the core structure of melatonin; it may be an endogenous ligand for PPARγ and may act as an agonist at 5-HT3 receptors.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18834449
| Cas No. |
1006-94-6 |
|---|---|
| Purity |
≥98% |
| Formula |
C9H9NO |
| Formula Wt. |
147.17 |
| Chemical Name |
5-Methoxy-1H-indole |
| IUPAC Name |
5-methoxy-1H-indole |
| Synonym |
Femedol |
| Melting Point |
52-55°C |
| Solubility |
Insoluble in water. |
| Appearance |
Slightly yellow crystalline |
Czimmerer Z, Varga T, Poliska S, et al. Identification of novel markers of alternative activation and potential endogenous PPARγ ligand production mechanisms in human IL-4 stimulated differentiating macrophages. Immunobiology. 2012 Dec;217(12):1301-14. PMID: 22954708.
Koike T, Hoashi Y, Takai T, et al. 1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT₂-selective agonists. J Med Chem. 2011 May 12;54(9):3436-44. PMID: 21473625.
