4-Dimethylaminopyridine
4-dimethylaminopyridine is an acyl transfer catalyst used as a coupling agent in peptide synthesis. This compound also exhibits cardiostimulatory inotropic activity.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1883394
| Cas No. |
1122-58-3 |
|---|---|
| Purity |
≥98% |
| Formula |
C7H10N2 |
| Formula Wt. |
122.17 |
| IUPAC Name |
N,N-dimethylpyridin-4-amine |
| Synonym |
DMAP; Pyridine, 4-(dimethylamino)-;N,N-Dimethyl- pyridin-4-amine |
| Melting Point |
108-110°C (lit.) |
| Solubility |
Soluble in methanol (0.1g/mL). |
| Appearance |
White to light yellow powder |
Wang J, Niu S, Zhao B, et al. Catalytic synthesis of sulfated polysaccharides. II: comparative studies of solution conformation and antioxidant activities. Carbohydr Polym. 2014 Jul 17;107:221-31. PMID: 24702939.
Lahsasni SA. Microwave- and ultrasound-assisted synthesis of some acyclonucleobases based on a uracil moiety using dmap as base. Nucleosides Nucleotides Nucleic Acids. 2013;32(8):439-52. PMID: 23895354.
Hayashi T, Sun Y, Tamura T, et al. Semisynthetic lectin-4-dimethylaminopyridine conjugates for labeling and profiling glycoproteins on live cell surfaces. J Am Chem Soc. 2013 Aug 21;135(33):12252-8. PMID: 23889132.
