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2-tert-Butyl-4-Hydroxyanisole

2-Tert-butyl-4-hydroxyanisole (2-BHA) is one component of butylated hydroxyanisole (BHA). This compound is commonly used as a food additive; it exhibits antioxidative activity. 2-BHA acts as a phase II enzyme inducer, increasing levels of glutathione and glutathione-S-transferase.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18832323

Cas No.

88-32-4

Purity

≥99%

Formula

C11H16O2

Formula Wt.

180.25

Chemical Name

2-(1,1-Di-methylethyl)4-methoxyphenol

IUPAC Name

3-tert-butyl-4-methoxyphenol

Synonym

2-BHA

Melting Point

69-71°C

Solubility

Insoluble in water. Soluble in ethanol, acetone, or DMSO.

Appearance

White Crystal Powder


product targets : Pyruvate Dehydrogenase inhibitors

Hwang GH, Jeon YJ, Han HJ, et al. Protective effect of butylated hydroxylanisole against hydrogen peroxide-induced apoptosis in primary cultured mouse hepatocytes. J Vet Sci. 2014 Oct 8. [Epub ahead of print]. PMID: 25293491.

Nishiya H, Haga T, Nozue N, et al. Effects of 2(3)-tert-butyl-4-hydroxyanisole pretreatment on cefpiramide binding to mouse glutathione S-transferases. Pharmacology. 1989;39(4):213-23. PMID: 2608720.

1-NM-PP1