10-Deacetyl-7-xylosyltaxol
Xylosyltaxol is a taxane found in species of Taxus. Like other taxanes, this compound may also promote microtubule polymerization and prevent microtubule depolymerization, exhibiting anticancer potential.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18831642
| Cas No. |
90332-63-1 |
|---|---|
| Purity |
≥97% |
| Formula |
C50H57NO17 |
| Formula Wt. |
943.98 |
| IUPAC Name |
(2α,5β,7β,10β,13α)-4-Acetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,10-dihydroxy-9-oxo-7-(β-D-xylopyranosyloxy)-5,20-epoxytax-11-en-2-yl benzoate |
| Synonym |
10-Deacetyl-7-xylosyl paclitaxel,10-Deacetylpaclitaxel 7-xyloside,10-Deacetyltaxol 7-xyloside |
| Appearance |
White Powder |
product targets : PAI-1 inhibitors
Hanson RL, Wasylyk JM, Nanduri VB, et al. Site-specific enzymatic hydrolysis of taxanes at C-10 and C-13. J Biol Chem. 1994 Sep 2;269(35):22145-9. PMID: 7915279.
Slichenmyer WJ, Von Hoff DD. New natural products in cancer chemotherapy. J Clin Pharmacol. 1990 Sep;30(9):770-88. PMID: 1980498.
